Evidence for ABL Amplification in Multiple Myeloma and Therapeutic Implications

Table 2

Genomic profiling of multiple myeloma cell lines by FISH.

Karyotype	NCI-H929	LP-1	U266	K562
BCR/ABL	2G2O	3G3O = 70%/4G4O = 30%	4G4O = 25%	Multiple F
c-Myc	3F	6F	4F = 27%
IGH	3F	2F6G2O	2F2O = 21%, FO = 79%
D13S319/RB1	3G3O	2G2O	2G2O = 19%, GO = 81%
p53/1q21	2G3O	3G8-10 O	2G6O = 26%, G2O = 74%

F: fusion; G: green; O: orange; 2G2O: normal.