Research Article

Nimotuzumab in the Treatment of Inoperable Esophageal Tumors of Epithelial Origin

Table 2

General information of adverse events.

Categories for patients1and AENimotuzumab treatment modalities
Nimo no. (%)Nimo + CT no. (%)Nimo + RT no. (%)Nimo + CT + RT no. (%)Total no. (%)

Patients with some AE10 (47.6)11 (52.4)8 (57.1)32 (72.7)61 (61)
Patients with some nimotuzumab-related AE1 (4.8)2 (9.5)0 (0)4 (9.1)7 (7)
Patients with some 3-4 severity degree AE2 (9.5)3 (14.3)3 (21.4)9 (20.5)17 (17)
Patients with some nimotuzumab-related 3-4 severity degree AE0 (0)1 (4.8)0 (0)0 (0)1 (1)
Patients with some serious AE3 (14.3)7 (33.3)2 (14.3)15 (34.1)27 (27)
Patients with some serious nimotuzumab-related AE0 (0)1 (4.8)0 (0)1 (2.3)2 (2)
Adverse events27 (100)31 (100)17 (100)154 (100)229 (100)
Nimotuzumab-related AE2 (7.4)6 (19.4)0 (0)6 (3.9)14 (6.1)
3-4 severity degree AE2 (7.4)5 (16.1)3 (17.6)13 (8.4)23 (10)
3-4 severity degree nimotuzumab-related AE0 (0)1 (3.2)0 (0)0 (0)1 (0.4)
Serious AE3 (11.1)10 (32.3)2 (11.8)24 (15.6)39 (17)
Serious AE related to nimotuzumab0 (0)1 (3.2)0 (0)2 (1.3)3 (1.3)

Nimo: nimotuzumab, CT: chemotherapy, RT: radiotherapy, AEs: adverse events. 1Subjects can be included in more than one category.