Comprehensive Network Analysis Identified SIRT7, NTRK2, and CHI3L1 as New Potential Markers for Intervertebral Disc Degeneration

Figure 6

Potential drugs and drug-target analysis of key IDD genes. (a) The distribution of network-regulated distance between drug and disease key genes. (b) Interaction results of drugs DB11986 and DB14723 with CHI3L1, NTRK2, and SIRT7 proteins. Among them, CHI3L1 protein was added sky blue surface, NTRK2 protein was added rosy brown surface, and SIRT7 protein was added sea green surface. The drug DB11986 was displayed as yellow, and DB14723 was displayed as orchid.

(a)

(b)