The Exosomal miR-1246 of Laryngeal Squamous Cell Carcinoma Induces Polarization of M2 Type Macrophages and Promotes the Invasiveness of Laryngeal Squamous Cell Carcinoma

Figure 4

TU212 cell-derived exosomes deliver miR-1246 to macrophages. (a) The miR-1246 expressions in HOK and TU212 cells or their corresponding exosomes were accessed by qRT-PCR assay. vs. HOK cells or H/exo. (b) The miR-1246 expressions in LSCC tissues or the corresponding exosomes were determined by qRT-PCR assay. vs. Normal tissues or Normal plasma-derived exosomes. (c) The miR-1246 expression in macrophages treated with HOK cell- or TU212 cell-derived exosomes at indicated times was assessed by qRT-PCR assay. vs. . (d) The miR-1246 expression in macrophages treated with HOK cell- or TU212 cell-derived exosomes was assessed by qRT-PCR assay. vs. . H/exo: HOK cell-derived exosomes; T/exo: TU212 cell-derived exosomes; M: Macrophages.

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