PLCD1-Induced DNA Damage Inhibits the Tumor Growth via Downregulating CDKs in Chondrosarcoma

Figure 2

PLCD1 knockdown promoted cell proliferation in vitro. (a) Establishment of the KD-PLCD1 SW1353 cell line. (b, c) Colony formation of the KD-PLCD1 cell line. (d) CCK-8 assay kit revealed a downregulation of cell proliferation by PLCD1 knockdown. (e) Western blotting revealed an upregulation of PCNA expression by PLCD knockdown. (f) Flow cytometry analysis revealed cell cycle blocking by PLCD knockdown.

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