Long Noncoding RNA XIST Promotes Resistance to Lenvatinib in Hepatocellular Carcinoma Cells via Epigenetic Inhibition of NOD2

Figure 2

lncXIST regulates cell death induced by lenvatinib in HCC cells. (a) HCC cells were transfected with as indicated for 24 h, then cells were treated with or without lenvatinib (10 μM) for another 24 h, and cell death was measured. (b) HCC cells were treated as described above, and caspase-3/7 activities were measured. (c) HepG2/R cells were transfected with si-NC or si-lncXIST and HepG2 cells were transfected with pcDNA or pc.lncXIST for 24 h, and indicated proteins were measured by western blots. The data was presented as . and .

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