Research Article
Comprehensive Analysis of Potential Biomarkers of Acute Lymphoblastic Leukemia in Children by Using a Competing Endogenous RNA Network
Table 1
Clinical characteristics of 261 patients with pediatric ALL.
| | Low risk () | High risk () | value | Overall () |
| | Age (years) | | | | | | Mean (SD) | 8.11 (5.40) | 7.63 (5.02) | 0.474 | 7.94 (5.26) | | Median [min, max] | 6.88 [0.918, 30.0] | 6.50 [0.0329, 16.2] | | 6.61 [0.0329, 30.0] | | Gender | | | | | | Female | 85 (50.3%) | 43 (46.7%) | 0.675 | 128 (49.0%) | | Male | 84 (49.7%) | 49 (53.3%) | | 133 (51.0%) | | White blood cell count | | | | | | <50 | 169 (100%) | 0 (0%) | <0.001 | 169 (64.8%) | | ≥50 | 0 (0%) | 92 (100%) | | 92 (35.2%) | | BCR-ABL1 fusion | | | | | | Yes | 0 (0%) | 5 (5.4%) | 0.00967 | 5 (1.9%) | | No | 169 (100%) | 87 (94.6%) | | 256 (98.1%) | | ETV6-RUNX1 fusion | | | | | | Yes | 19 (11.2%) | 2 (2.2%) | 0.0195 | 21 (8.0%) | | No | 150 (88.8%) | 90 (97.8%) | | 240 (92.0%) | | TCF3_HLF | | | | | | Yes | 15 (8.9%) | 7 (7.6%) | 0.905 | 22 (8.4%) | | No | 154 (91.1%) | 85 (92.4%) | | 239 (91.6%) | | Trisomy of both chromosomes 4 and 10 | | | | | | Yes | 14 (8.3%) | 7 (7.6%) | 1 | 21 (8.0%) | | No | 155 (91.7%) | 85 (92.4%) | | 240 (92.0%) | | TCF3PBX1 | | | | | | Yes | 15 (8.9%) | 7 (7.6%) | 0.905 | 22 (8.4%) | | No | 154 (91.1%) | 85 (92.4%) | 239 (91.6%) | | | Overall survival time (year) | | | | | | Mean (SD) | 4.70 (3.26) | 4.94 (3.70) | 0.6 | 4.78 (3.41) | | Median [min, max] | 3.33 [0.271, 14.5] | 3.21 [0.0685, 12.0] | | 3.33 [0.0685, 14.5] | | Missing | 1 (0.6%) | 3 (3.3%) | | 4 (1.5%) | | Event free survival time (years) | | | | | | Mean(SD) | 2.80 (2.19) | 4.05 (3.76) | 0.00475 | 3.24 (2.89) | | Median [min, max] | 2.38 [0.211, 11.2] | 2.54 [0.0685, 12.0] | | 2.39 [0.0685, 12.0] | | Missing | 4 (2.4%) | 3 (3.3%) | | 7 (2.7%) |
|
|
