Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis

<div>TC-secreted FGD5-AS1 metastasizes to HUVECs. (a) The level of FGD5-AS1 in the TC cell line was analyzed using qRT-PCR. (b) Expression of FGD5-AS1 in SW1736 cells transfected with vector-FGD5-AS1 or vector-NC and qRT-PCR detection of exosomes derived therefrom. (c) Expression of FGD5-AS1 in KAT18 cells transfected with vector-FGD5-AS1 or vector-NC and qRT-PCR detection of its derived exosomes. (d) qRT-PCR analysis of FGD5-AS1 expression in HUVECs incubated with exosomes from TC cells for 2, 12, 24, and 48 hours. 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Journal of Oncology

fig2

Figure 2

Figure 2: Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis 

Figure 2 | Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis 