Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis

<div>Overexpression of FGD5-AS1 enhances HUVEC proliferation, migration, angiogenesis, and permeability. (a) The proliferation of HUVECs after transfection with the FGD5-AS1 overexpression plasmid was detected by the CCK-8 method. (b) The effect of FGD5-AS1 on HUVEC migration was detected by the transwell method. (c) Western blot detection of VEGF, VE-cadherin, ZO-1, occludin, and claudin5 protein levels in HUVECs after overexpression of FGD5-AS1. (d) Immunofluorescence analysis of VE-cadherin expression after FGD5-AS1 transfection of HUVECs. 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Journal of Oncology

fig3

Figure 3

Figure 3: Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis 

Figure 3 | Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis 