Hypoxia Confers Tumor with a Higher Immune Infiltration but Lower Mutation Burden in Gastrointestinal Cancer

Figure 1

Gastrointestinal cancer clustered into two subtypes based on hypoxic signature. (a) Rank survey of the parameter (r) in TCGA samples by NMF. (b) Clustering of 1,043 gastrointestinal cancers in the TCGA by NMF. (c) PCA plot of TCGA samples according to the subtypes identified by NMF. (d) Rank survey of the parameter (r) in GEO samples by NMF. (e) Clustering of 885 gastrointestinal cancers in the GEO by NMF. (f) PCA plot of GSE39582 and GSE62254 samples.

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