Hypoxia Confers Tumor with a Higher Immune Infiltration but Lower Mutation Burden in Gastrointestinal Cancer

Figure 2

The association of MSI-H, hypermutation, and immune status between the hypoxic and normoxic groups. (a) Immune score, stromal score, and estimate score calculated by the estimate algorithm were visualized by heatmap according to hypoxic and normoxic groups in TCGA cohorts. (b) Immune score, stromal score, and estimate score were visualized by heatmap according to hypoxic and normoxic groups in GEO cohorts. The hypoxic group had a lower TMB but significantly higher immune and stromal cell infiltration.

(a)

(b)