Efficacy of Surgery in Patients with Stage I Primary Parotid Gland Lymphoma: A Population-Based Study

Table 4

Univariate and multivariate analysis of overall survival.

Characteristics	Univariate analysis HR (95% CI)		Multivariate analysis HR (95% CI)
Age
≤65	1		1
>65	7.335 (5.397–9.969)	<0.001	7.248 (5.287–9.936)	<0.001
Sex
Female	1
Male	1.045 (0.817–1.336)	0.726	NA	NA
Race
White	1		1
Black	0.571 (0.339–0.962)	0.035	0.725 (0.425–1.237)	0.239
Other	0.481 (0.262–0.881)	0.018	0.469 (0.255–0.864)	0.015
Marital status
No married	1		1
Married	0.611 (0.480–0.776)	<0.001	0.646 (0.505–0.828)	0.001
Laterality
Right	1
Left	1.080 (0.848–1.376)	0.532	NA	NA
Bilateral	0.836 (0.309–2.265)	0.724	NA	NA
Histology
MALT	1
DLBCL	2.548 (1.852–3.505)	<0.001	1.900 (1.3702.636)	<0.001
FL	1.572 (1.141–2.165)	0.006	1.189 (0.860–1.644)	0.295
Other	1.605 (1.133–2.275)	0.008	1.657 (1.157–2.373)	0.006
Year of diagnosis
1998–2003	1		1
2004–2009	0.815 (0.620–1.073)	0.145	0.976 (0.737–1.294)	0.868
2010–2015	0.531 (0.345–0.817)	0.004	0.536 (0.347–0.829)	0.005
Methods
No surgery	1		1
Local tumor excision	0.813 (0.568–1.163)	0.257	0.947 (0.655–1.37)	0.773
Superficial parotidectomy	0.687 (0.490–0.966)	0.031	0.697 (0.492–0.989)	0.043
Total parotidectomy	0.598 (0.437–0.818)	0.001	0.682 (0.492–0.945)	0.021
Radiation
No	1
Yes	0.800 (0.629–1.019)	0.070	NA	NA
Chemotherapy
No	1
Yes	0.948 (0.730–1.232)	0.691	NA	NA