Efficacy of Surgery in Patients with Stage I Primary Parotid Gland Lymphoma: A Population-Based Study

Table 5

Univariate and multivariate analysis of cancer-specific survival.

Characteristics	Univariate analysis HR (95% CI)		Multivariate analysis HR (95% CI)
Age
≤65	1
>65	3.475 (2.323–5.198)	<0.001	3.634 (2.389–5.528)	<0.001
Sex
Female	1
Male	1.126 (0.772–1.641)	0.538	NA	NA
Race
White	1
Black	1.040 (0.557–1.940)	0.902	NA	NA
Other	0.343 (0.109–1.083)	0.068	NA	NA
Marital status
No married	1
Married	0.549 (0.378–0.795)	0.002	0.663 (0.453–0.971)	0.035
Laterality
Right	1
Left	1.432 (0.976–2.099)	0.066	NA	NA
Bilateral	1.764 (0.547–5.688)	0.342	NA	NA
Histology
MALT	1
DLBCL	4.045 (2.413–6.783)	<0.001	3.471 (2.036–5.917)	<0.001
FL	1.973 (1.131–3.442)	0.017	1.665 (0.951–2.916)	0.074
Other	3.630 (2.166–6.083)	<0.001	3.513 (2.061–5.989)	<0.001
Year of diagnosis
1998–2003	1
2004–2009	0.746 (0.493–1.128)	0.165	0.827 (0.542–1.262)	0.401
2010–2015	0.410 (0.218–0.772)	0.006	0.397 (0.209–0.753)	0.005
Methods
No surgery	1
Local tumor excision	0.727 (0.420–1.258)	0.255	0.935 (0.53–1.647)	0.815
Superficial parotidectomy	0.717 (0.436–1.179)	0.190	0.840 (0.506–1.395)	0.502
Total parotidectomy	0.429 (0.258–0.715)	0.001	0.573 (0.339–0.968)	0.037
Radiation
No	1
Yes	0.663 (0.454–0.969)	0.034	0.607 (0.410–0.898)	0.012
Chemotherapy
No	1
Yes	1.287 (0.876–1.891)	0.198	NA	NA