WDR72 Enhances the Stemness of Lung Cancer Cells by Activating the AKT/HIF-1α Signaling Pathway

Figure 4

WDR72 knockdown restrains the tumorigenesis of LCSCs. (a) The tumor volume of A549 stem cell-injected mice. (b) The tumor volume of SPCA-1 stem cell-injected mice. (c) The tumor weight of A549 stem cell-injected mice. (d) The tumor weight of SPCA-1 stem cell-injected mice. (e) Tumors excised from A549 stem cell-injected mice. (f) Tumors excised from SPCA-1 stem cell-injected mice. (g) Abundance of proliferation-, EMT-, and apoptosis-associated genes in tumor tissues of A549 stem cell-injected mice. (h) Abundance of proliferation-, EMT-, and apoptosis-associated genes in tumor tissues of SPCA-1 stem cell-injected mice.

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