Research Article

circRNA TCFL5 Promote Esophageal Cancer Progression by Modulating M2 Macrophage Polarization via the miR-543-FMNL2 Axis

Figure 5

circRNA TCFL5 promotes cell proliferation, migration, and invasion of Eca109 and KYSE150 by modulating the miR-543/FMNL2 axis. (a) CCK-8 analysis was used to detect the proliferation of Eca109 and KYSE150 cells affected by miR-543 or FMNL2; (b, c) transwell assay was performed to detect the migration and invasion of Eca109 and KYSE150 cells affected by miR-543 or FMNL2; , miR-543 inhibitors, or over-FMNL2 groups vs. NC group; ##, miR-543 mimics or Sh-FMNL2 groups vs. NC group; (d) CCK-8 analysis was used to detect the proliferation of Eca109 and KYSE150 cells affected by circRNA TCFL5 and reversed by miR-543 or FMNL2; (e, f) transwell assay was performed to detect the migration and invasion of Eca109 and KYSE150 cells affected by circRNA TCFL5 and reversed by miR-543 or FMNL2. Data are shown as the . , over-circRNA TCFL5 vs. NC group.
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