Research Article
Correlation Study on the Expression of INSR, IRS-1, and PD-L1 in Nonsmall Cell Lung Cancer
Table 2
The relationship between INSR, IRS-1 expression, and clinicopathological features in NSCLC.
| | Clinicopathological features | Total | INSR (%) | | IRS-1 (%) | | | + | - | + | - |
| | Gender | Man | 26 | 17 (65.4) | 9 (34.6) | 0.878 | 14 (33.3) | 12 (33.3) | 0.532 | | Female | 19 | 12 (63.2) | 7 (36.8) | 12 (63.2) | 7 (36.8) |
| | Age | <60 | 20 | 13 (65.0) | 7 (35.0) | 0.944 | 12 (60.0) | 8 (40.0) | 0.787 | | ≥60 | 25 | 16 (64.0) | 9 (36.0) | 14 (56.0) | 11 (44.0) |
| | Pathological type | Squamous carcinoma | 12 | 7 (58.3) | 5 (41.7) | 0.606 | 5 (41.7) | 7 (58.3) | 0.187 | | Adenocarcinoma | 33 | 22 (66.7) | 11 (33.3) | 21 (63.6) | 12 (36.4) |
| | TNM stage | | 19 | 10 (52.6) | 9 (47.4) | 0.157 | 12 (63.2) | 7 (36.8) | 0.532 | | 26 | 19 (73.1) | 7 (26.9) | 14 (53.8) | 12 (46.2) |
| | Tissue differentiation | Moderately-well | 27 | 14 (51.9) | 13 (48.1) | 0.031 | 16 (59.3) | 11 (40.7) | 0.805 | | Poorly | 18 | 15 (83.3) | 3 (16.7) | 10 (55.6) | 8 (44.4) |
| | Lymph node metastasis | No | 18 | 11 (61.1) | 7 (38.9) | 0.712 | 10 (55.6) | 8 (44.4) | 0.309 | | Yes | 27 | 15 (55.6) | 12 (44.4) | 19 (70.4) | 8 (29.6) |
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