Tumour: Fibroblast Interactions Promote Invadopodia-Mediated Migration and Invasion in Oral Squamous Cell Carcinoma

Figure 4

The expression of Tks5 and that of αSMA were associated with poor survival. Immunohistochemical detection of Tks5 and αSMA was carried out on a cohort of 60 patients with OSCC. The expression of the two markers was assessed by blinded reviewers and categorized as low (Tks5– or αSMA–) or high (Tks5+ or αSMA+). (a) Representative images of high- and low-expression cases. (b)–(d): The 5-year survival rates were calculated by the Kaplan–Meier method and compared by log-rank test.

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