Hesperidin Inhibits the p53-MDMXInteraction-Induced Apoptosis of Non-Small-Cell Lung Cancer and Enhances the Antitumor Effect of Carboplatin

Figure 3

Hesperetin induced p53-dependent apoptosis by inhibiting the expression of MDMX. (a) MDMX expression detection after different treatments. (b) Detection of the p53 expression after different treatments. (c) PIG3 expression detection after different treatments. (d) PUMA expression detection after different treatments. (e) Bax expression detection after different treatments. (f) Bcl-2 expression detection after different treatments. Error bars represent the standard deviations of three independent experiments. , P < 0.01; , P < 0.01. Mean ± SD are shown, n = 3.

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