Hesperidin Inhibits the p53-MDMXInteraction-Induced Apoptosis of Non-Small-Cell Lung Cancer and Enhances the Antitumor Effect of Carboplatin

Figure 5

Hesperetin increased the antitumor activity of carboplatin. (a) Tunel to detect cell apoptosis (carboplatin: 40 μM; hesperidin: 10 μM). (b) CCK-8 experiment to detect cell proliferation after different treatments. (c) Transwell experiment to detect cell-invasion ability after different treatments. Error bars represent the standard deviations of three independent experiments. Scale bar = 100 μm. , P < 0.01. HPF: high-power field. Mean ± SD are shown, n = 3.

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