Screening of Serum Exosomal miRNAs as Diagnostic Biomarkers for Gastric Cancer Using Small RNA Sequencing

Table 5

Correlation of serum exosomal miR-10401-3p, miR-1255-5p, and miR-6736-5p expression (ΔCt) and clinicopathological features of patients with GC

Features	Number	miR-10401-3p		miR-1255-5p		miR-6736-5p
		Mean ± SD	value	Mean ± SD	value	Mean ± SD	value
Age (years)
≥60	12	1.04 ± 1.02	0.70	0.07 ± 0.05	0.755	0.32 ± 0.18	0.727
<60	12	0.87 ± 1.05		0.06 ± 0.05		0.35 ± 0.29
Gender
Male	14	0.86 ± 1.01	0.591	0.058 ± 0.045	0.643	0.35 ± 0.22	0.748
Female	10	1.09 ± 1.06		0.068 ± 0.05		0.31 ± 0.27
Tumor size
5 cm	11	1.49 ± 1.25	0.029	0.59 ± 0.51	0.766	0.38 ± 0.27	0.309
<5 cm	13	0.51 ± 0.44		0.65 ± 0.49		0.28 ± 0.20
Tumor differentiation
Well	5	0.52 ± 0.56	0.288	0.49 ± 1.123	0.526	0.24 ± 0.20	0.330
Moderate + poor	19	1.07 ± 1.09		0.07 ± 0.05		0.36 ± 0.24
TNM stage
I–II	6	0.73 ± 0.48	0.533	0.05 ± 0.02	0.369	0.15 ± 0.18	0.03
III–IV	18	1.03 ± 1.14		0.07 ± 0.05		0.39 ± 0.22
Lymphatic node metastasis
Negative	15	0.93 ± 0.96	0.855	0.04 ± 0.02	0.004	0.26 ± 0.18	0.045
Positive	9	1.01 ± 1.17		0.11 ± 0.05		0.46 ± 0.28