Diosmetin Affects Gene Expression on Human Lung Adenocarcinoma Cells

Table 2

Top 10 differentially expressed mRNAs in A549 cells treated with diosmetin.

Upregulated mRNAs	Times of difference	Downregulated mRNAs	Times of difference
Glucoside xylosyltransferase 2	25.52	Phospholipase A2, group VI	6.90
Interleukin 7 receptor	20.37	Mucin 6, oligomeric mucus/gel forming	6.86
Collagen, type V, alpha 1	18.84	3-hydroxy-3-methylglutaryl-CoA reductase	6.84
Bone morphogenetic protein 5	13.83	Cytochrome P450, family 51, subfamily A, polypeptide 1	6.19
Carboxypeptidase A4	12.71	Squalene epoxidase	5.55
Fibroblast growth factor 21	12.50	Low density lipoprotein receptor	4.24
Insulin-like growth factor 1 (somatomedin C)	9.64	G protein-coupled receptor 180	4.04
Interleukin 6 (interferon, beta 2)	6.52	Neuropilin 1	3.88
p53-responsive gene 1	5.86	Myelin basic protein	3.85
GTP binding protein 2	2.80	Glutamate receptor interacting protein 2	3.75