Research Article
Diosmetin Affects Gene Expression on Human Lung Adenocarcinoma Cells
Table 3
Top 10 differentially expressed mRNAs in HCC827 cells treated with diosmetin.
| Upregulated mRNAs | Times of difference | Downregulated mRNAs | Times of difference |
| Deiodinase, iodothyronine, type II | 77.62 | Calbindin 2 | 39.31 | Zinc finger protein 804A | 50.17 | Keratin 5 | 16.11 | p53-responsive gene 1 | 5.86 | Insulin induced gene 1 | 11.14 | CD22 molecule | 4.39 | Calpain 8 | 10.00 | Low density lipoprotein receptor-related protein 1 | 4.34 | Amphiregulin | 8.29 | Quiescin Q6 sulfhydryl oxidase 1 | 3.30 | Keratin 12 | 3.73 | ATPase, class II, type 9A | 3.25 | Neuropilin (NRP) and tolloid- (TLL-) like 2 | 3.69 | CD274 molecule | 3.09 | GATA zinc finger domain containing 2A | 3.67 | SMAD family member 9 | 3.03 | Cyclin E2 | 3.62 | Tumor necrosis factor receptor superfamily, member 13C | 2.78 | Pyruvate dehydrogenase phosphatase catalytic subunit 2 | 3.57 |
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