Research Article

Diosmetin Affects Gene Expression on Human Lung Adenocarcinoma Cells

Table 3

Top 10 differentially expressed mRNAs in HCC827 cells treated with diosmetin.

Upregulated mRNAsTimes of differenceDownregulated mRNAsTimes of difference

Deiodinase, iodothyronine, type II77.62Calbindin 239.31
Zinc finger protein 804A50.17Keratin 516.11
p53-responsive gene 15.86Insulin induced gene 111.14
CD22 molecule4.39Calpain 810.00
Low density lipoprotein receptor-related protein 14.34Amphiregulin8.29
Quiescin Q6 sulfhydryl oxidase 13.30Keratin 123.73
ATPase, class II, type 9A3.25Neuropilin (NRP) and tolloid- (TLL-) like 23.69
CD274 molecule3.09GATA zinc finger domain containing 2A3.67
SMAD family member 93.03Cyclin E23.62
Tumor necrosis factor receptor superfamily, member 13C2.78Pyruvate dehydrogenase phosphatase catalytic subunit 23.57