Research Article

Longitudinal Trajectories of Memory Performance in Patients with Early-Stage Breast Cancer

Table 2

Cancer-related demographics and treatment at baseline.

Chemotherapy+hormone therapy group Hormone therapy group Chemotherapy group Control group

Menopausal status (percentage of group)
 Premenopausal15 (45%)14 (64%)10 (71%)--
 Postmenopausal18 (55%)8 (36%)4 (29%)--
Serum estradiol
(Median (range))
15 (2-274)
19 (2-132)
14 (2-286)
14 (2-130)
Expression of ER and/or PR
 Positive33220--
 Negative0014--
HER2
(percentage of group)
 Positive4 (12%)0 (0%)3 (21%)--
 Negative29 (88%)21 (95%)11 (79%)--
Treatment
(percentage of group)
 Chemotherapy
  Anthracycline+taxane19 (58%)--9 (64%)--
  Paclitaxel±cyclophosphamide12 (36%)--3 (21%)--
  Other2 (6%)--2 (14%)--
 Hormone therapy
  Aromatase inhibitor18 (54%)15 (68%)----
  Tamoxifen14 (42%)3 (13%)----
  Aromatase inhibitor+tamoxifen1 (3%)4 (18%)----

Cancer treatment-related demographics at baseline. ER: estrogen receptor; PR: progesterone receptor; : number of subjects; df: degrees of freedom. Chemotherapy regimens consisted of anthracycline+taxane (doxorubicin/cyclophosphamide followed by paclitaxel±trastuzumab, paclitaxel/carboplatin followed by doxorubicin/cyclophosphamide±trastuzumab, paclitaxel/neratinib followed by doxorubicin/cyclophosphamide±trastuzumab, or paclitaxel followed by doxorubicin/cyclophosphamide), cyclophosphamide+paclitaxel (paclitaxel/carboplatin±trastuzumab or paclitaxel/trastuzumab), or other (gemcitabine/carboplatin followed by paclitaxel/carboplatin). Hormone therapy regimens consisted of aromatase inhibition (anastrozole, letrozole, or exemestane) or tamoxifen or both. One participant was missing HER2 data.