Target Protein for Xklp2 Functions as Coactivator of Androgen Receptor and Promotes the Proliferation of Prostate Carcinoma Cells

Figure 2

TPX2 enhanced the mRNA or protein expression of AR’s down gene PSA in LNCaP cells. LNCaP cells were transfected with plasmids (control, TPX2, or siTPX2). Then, cells were harvested for qPXR or Western blot experiments. The mRNA level of PSA was examined by qPCR and shown as (a). The protein level of PSA or TPX2 was examined by Western blot, and the results were shown as the images of Western blot (b) or the quantitative results of the images (c–e). .

(a)

(b)

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(e)