Journal of Oncology / 2022 / Article / Tab 3 / Research Article
Exploration of Prognostic Immune-Related Genes and lncRNAs Biomarkers in Kidney Renal Clear Cell Carcinoma and Its Crosstalk with Acute Kidney Injury Table 3 Correlation between the training cohort, validation cohort, and total cohort clinical features and the risk scores of the predictive model based on immune-related lncRNAs.
Variables Training cohort (n = 264) Validation cohort (n = 262) Total cohort (n = 536) High risk (%) Low risk (%) χ 2 High risk (%) Low risk (%) χ 2 High risk (%) Low risk (%) χ 2 Age 0.017 0.897 0 1 0.034 0.854 ≤65 86 (65.15%) 88 (66.67%) 86 (65.65%) 87 (66.41%) 172 (65.4%) 175 (66.54%) >65 46 (34.85%) 44 (33.33%) 45 (34.35%) 44 (33.59%) 91 (34.6%) 88 (33.46%) Gender 0 1 0 1 0 1 Female 44 (33.33%) 44 (33.33%) 47 (35.88%) 48 (36.64%) 91 (34.6%) 92 (34.98%) Male 88 (66.67%) 88 (66.67%) 84 (64.12%) 83 (63.36%) 172 (65.4%) 171 (65.02%) Grade 0.962 0.327 1.880 0.170 3.056 0.08 G1-2 54 (40.91%) 62 (46.97%) 56 (42.75%) 67 (51.15%) 110 (41.83%) 129 (49.05%) G3-4 78 (59.09%) 68 (51.52%) 73 (55.73%) 60 (45.8%) 151 (57.41%) 128 (48.67%) Unknown 0 (0%) 2 (1.52%) 2 (1.53%) 4 (3.05%) 2 (0.76%) 6 (2.28%) Stage 8.339 0.004 0.666 0.414 7.41 0.006 Stages I-II 67 (50.76%) 91 (68.94%) 76 (58.02%) 84 (64.12%) 143 (54.37%) 175 (66.54%) Stages III-IV 65 (49.24%) 41 (31.06%) 53 (40.46%) 46 (35.11%) 118 (44.87%) 87 (33.08%) Unknown / / 2 (1.53%) 1 (0.76%) 2 (0.76%) 1 (0.38%) T classification 5.196 0.023 2.450 0.117 7.918 0.005 T1-2 72 (54.55%) 91 (68.94%) 80 (61.07%) 93 (70.99%) 152 (57.79%) 184 (69.96%) T3-4 60 (45.45%) 41 (31.06%) 51 (38.93%) 38 (29.01%) 111 (42.21%) 79 (30.04%) M classification 11.324 <0.001 0 1 5.99 0.014 M0 94 (71.21%) 119 (90.15%) 97 (74.05%) 108 (82.44%) 191 (72.62%) 227 (86.31%) M1 28 (21.21%) 9 (6.82%) 20 (15.27%) 21 (16.03%) 48 (18.25%) 30 (11.41%) Unknown 10 (7.58%) 4 (3.03%) 14 (10.69%) 2 (1.53%) 24 (9.13%) 6 (2.28%) N classification 1.292 0.256 0.145 0.703 0.016 0.898 N0 61 (46.21%) 59 (44.7%) 61 (46.56%) 57 (43.51%) 122 (46.39%) 116 (44.11%) N1 5 (3.79%) 1 (0.76%) 4 (3.05%) 6 (4.58%) 9 (3.42%) 7 (2.66%) Unknown 66 (50%) 72 (54.55%) 66 (50.38%) 68 (51.91%) 132 (50.19%) 140 (53.23%)
