[Retracted] Meta-Study of the Clinical Effect of Conservative Treatment in Uterine Fibroids

Table 4

Comparison of Various drugs for fibroid treatments.

Parameters	Leuprolide acetate	Mifepristone	Ulipristal acetate	Herbal	Gestagens
Drug type	GnRh analogs	Progesterone receptor antagonist	Progesterone receptormodulator		Progesterone receptor antagonist
Base of evidence	1RCT	3RCT	3RCT	21RCT	3RCT
Participants count	300	125	750	2000	100
Remarks	High quality	Restricted participants	High quality	Poor quality	Restricted participants
Volume reduction of fibroids	52%	NIL	59.5%	Marginal	Marginal
Symptoms	85%	99%	NIL	No Data	Yes
Fertility improvement	73%	72%	66%	79%	75%
Frequently used drug	Vasomotor Concerns	Uterine cramp	Vasomotor concerns	Body ache	Abdomen pain