MiR-300 Alleviates Cell Proliferation and Migration and Facilitates Cell Apoptosis by Targeting c-Met in Gastric Cancer

Figure 2

c-Met promotes GC cell proliferation and migration and reduced cell apoptosis. (a) WB analysis of c-Met levels in MKN-45 cell line after transfection with c-Met siRNA or c-Met plasmid. (b–c) qRT-PCR analysis of c-Met levels in MKN-45 cell line after transfection with c-Met siRNA or c-Met plasmid. (d) CCK-8 assay analysis of MKN-45 proliferation after transfection with c-Met siRNA or c-Met plasmid. (e and f) Transwell assay analysis of MKN-45 cell migration after transfection with c-Met siRNA or c-Met plasmid. Scar bar: 20 μm. (g and h) MKN-45 cell apoptosis was assayed by flow cytometric analysis after transfection with c-Met siRNA or c-Met plasmid and treated with LPS. , ; ; .

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