MiR-300 Alleviates Cell Proliferation and Migration and Facilitates Cell Apoptosis by Targeting c-Met in Gastric Cancer

Figure 4

miR-300 suppresses GC cell proliferation and migration and increased cell apoptosis. (a) CCK-8 assay analysis of MKN-45 proliferation after transfection with miR-300 mimic or inhibitor. (b and c) Transwell assay analysis of MKN-45 cell migration after transfection with miR-300 mimic or inhibitor. Scar bar: 20 μm. (d and e) MKN-45 cell apoptosis was assayed by flow cytometric analysis after transfection with miR-300 mimic or inhibitor and treated with LPS. (f) CCK-8 assay analysis of MKN-45 proliferation after co-transfection with miR-300 mimic and c-Met plasmid. (g and h) Transwell assay analysis of MKN-45 cell migration after co-transfection with miR-300 mimic and c-Met plasmid. Scar bar: 20 μm. (i and j) MKN-45 cell apoptosis was assayed by flow cytometric analysis after co-transfection with miR-300 mimic and c-Met plasmid and treated with LPS. , ; ; .

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