Research Article

Establishment and Validation of a Nomogram Prognostic Model for Epithelioid Hemangioendothelioma

Table 1

General clinical characteristics of the EHE patients.

CharacteristicAll patients (%)Training group (%)Validation group (%)

Age1.6080.109
Sex0.0001.000
 Female300 (58.9)211 (58.6)89 (58.6)
 Male212 (41.1)149 (41.4%)63 (41.4%)
Race4.8360.089
 Black56 (10.9)43 (11.9%)13 (8.6%)
 Other (Asian)35 (6.8)30 (8.3%)6 (3.9%)
 White420 (82.0)287 (79.7%)133 (87.5%)
Degree of differentiation0.9620.644
 Poor (grade III or IV)47 (9.2)35 (9.7%)12 (7.9%)
 Unknown378 (73.8)267 (74.2%)111 (73%)
 Good (grade I or II)87 (17.0)58 (16.1%)29 (19.1%)
Staging1.5430.677
 Distant187 (36.5)133 (36.9%)54 (35.5%)
 Localized146 (28.5)104 (28.9%)42 (27.6%)
 Regional98 (19.1)64 (17.8%)34 (22.4%)
 Unknown81 (15.8)59 (16.4%)22 (14.5%)
Primary location3.380.50
 Bone (soft tissue)121 (23.6)87 (24.2%)34 (22.4%)10
 Head and neck40 (7.8)29 (8.1%)11 (7.2%)
 Liver131 (25.6)84 (23.3%)47 (30.9%)
 Lung124 (24.2)89 (24.7%)35 (23%)
 Other parts98 (18.8)71 (19.7%)25 (16.4%)
Surgery2.1170.359
 No217 (42.4)149 (41.4%)68 (44.7%)
 Unknown32 (6.3)26 (7.2%)6 (3.9%)
 Yes263 (51.4)185 (51.4%)78 (51.3%)
Chemotherapy0.0760.828
 No373 (72.9)261 (72.5%)112 (73.7%)
 Yes139 (27.1)99 (27.5%)40 (26.3%)
Radiotherapy1.7220.215
 No392 (76.6)267 (74.2%)121 (79.6%)
 Yes120 (23.4)93 (25.8%)31 (20.4%)

EHE: epithelioid hemangioendothelioma; SD: standard deviation.