Additional Postoperative Radiotherapy Prolonged the Survival of Patients with I-IIA Small Cell Lung Cancer: Analysis of the SEER Database

Figure 4

Evaluation and validation of performance of developed nomogram. (a) AUC of nomogram for the prediction of 10-year OS rate. (b) Time-dependent AUC of using the proposed nomogram to predict the OS within 10 years. The gray area represents the 0.95 CI of AUC at each time point. The dotted blue line reflects 0.65 AUC value. (c–e) Calibration curve for 3/5/10-year OS rate for patients with stage I-IIA SCLC. Calibration plots reflected the consistency between predicted OS probability by the nomogram and actual OS probability. (f–h) DCA plots of 3/5/10-year OS probability rate by the developed nomogram. Greater area among three curves accompanied with greater clinical practicability. (i) Frequency density diagram of AUC values using the nomogram for 10-year OS rate prediction based on the bootstrapping method (resample = 1,000). The CI of population parameter of AUC for 10-year survival prediction was evaluated as [0.7085, 0.9011]. ROC: receiver operating characteristic curve; AUC: area under the curve; OS: overall survival; DCA: decision curve analysis.

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