PFKFB3 Increases IL-1<i>β</i> and TNF-<i>α</i> in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer

<div>The p65 activation in CAC. (a) The phosphorylation of p65 detected in PFKFB3 overexpression and knockdown. (b) The nuclear translocation of p65 detected in PFKFB3 overexpression and knockdown; scar bar = 20 <i>μ</i>m. (c)-(d) The expression of IL-1<i>β</i> and TNF-<i>α</i> level by PFKFB3 overexpression and p65 knockdown in IECs. (e) The proliferation of CRC by PFKFB3 overexpression and p65 knockdown in IECs. 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Journal of Oncology

fig3

Figure 3

Figure 3: PFKFB3 Increases IL-1<i>β</i> and TNF-<i>α</i> in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer 

Journal of Oncology

PFKFB3 Increases IL-1β and TNF-α in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer

Figure 3