PFKFB3 Increases IL-1<i>β</i> and TNF-<i>α</i> in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer

<div>The PFK158 reduces cell proliferation, migration, and invasion. (a)-(b) The IL-1<i>β</i> and TNF-<i>α</i> expression level detected in PFK158 treatment. (c) The proliferation of CRC by LPS stimulation and PFK158 treatment in IECs. (d) The migration of CRC by LPS stimulation and PFK158 treatment in IECs; scar bar = 100 <i>μ</i>m. (e) The invasion of CRC by LPS stimulation and PFK158 treatment in IECs; scar bar = 50 <i>μ</i>m. 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Journal of Oncology

fig4

Figure 4

Figure 4: PFKFB3 Increases IL-1<i>β</i> and TNF-<i>α</i> in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer 

Journal of Oncology

PFKFB3 Increases IL-1β and TNF-α in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer

Figure 4