Research Article

Prognostic Evaluation Based on Dual-Time 18F-FDG PET/CT Radiomics Features in Patients with Locally Advanced Pancreatic Cancer Treated by Stereotactic Body Radiation Therapy

Table 1

Clinical characteristics of the patients in the training cohort and the validation cohort. #Data are the number of patients and data in parentheses are the ratio.

VariableTraining cohort (n = 46)Validation cohort (n = 24) value

Age (years)68 (26, 82)67 (45, 84)0.985

Sex#0.156
 Male31 (67.4%)12 (50.0%)
 Female15 (32.6%)12 (50.0%)

T stage#0.345
 12 (4.3%)1 (4.2%)
 212 (26.1%)5 (20.8%)
 315 (32.6%)13 (54.2%)
 417 (32.7%)5 (20.8%)

N stage#0.102
 030 (65.2%)10 (41.7%)
 116 (34.8%)14 (58.3%)

ECOG#0.458
 08 (17.4%)7 (29.2%)
 123 (50.0%)9 (37.5%)
 215 (32.6%)8 (33.3%)

CA19-9365 (2, 2125)132 (2, 1200)0.504

Longest diameter (cm)3.6 (1.5, 7.5)3.9 (1.0, 6.3)0.268

Location#0.783
 Head34 (73.9%)17 (70.8%)
 Body/distal12 (26.1%)7 (29.2%)

Chemotherapy#0.312
 029 (63.0%)18 (75.0%)
 117 (37.0%)16 (25.0%)

Dose37.2 (30, 46.8)36 (30, 46.8)0.454

OS (month)15.4 (7.5, 56.8)14 (10.6, 43.9)0.449

Data are the median and data in parentheses are the range. Chi-square test and Mann–Whiney U test are used to compare the difference between categorical and continuous variables in the training cohort and the validation cohort, respectively. ECOG, eastern cooperative oncology group; CA19-9, carbohydrate antigen 19–9; dose, radiotherapy dose (Gy).