Research Article

A Clinical Radiomics Nomogram Was Developed by Integrating Radiomics Signatures and Clinical Variables to Distinguish High-Grade ccRCC from Type 2 pRCC

Figure 3

Radiomics features were selected using a minor absolute shrinkage and selection operator (LASSO) regression model. (a). The LASSO model’s tuning parameter (λ) was determined using a minimum criterion 10-fold cross-validation criterion. The dotted vertical lines indicate the optimal values of the LASSO tuning parameter (λ), and a value λ of 0.082 with ln (λ) = −2.501 was chosen. (b). LASSO coefficient of the 427 radiomics features. A coefficient profile plot was generated versus the selected ln (λ) value using 10-fold cross-validation; the vertical line was plotted with eight chosen radiomics features.
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