Genomic and Immunological Characterization of Pyroptosis in Lung Adenocarcinoma

Figure 1

Genetic and expression variations of PRGs in TCGA cohort. (a) The waterfall diagram shows the somatic mutations of 27 PRGs from the LUAD sample of TCGA. (b) Kaplan-Meier survival plot of two groups with mutant and wild type (WT) PRGs. (c) GSEA of hallmark pathways by comparing mutant group to WT group in LUAD samples. (d) The CNV fraction of PRGs in LUAD samples. (e) Comparison of CNV difference in 27 PRGs in LUAD samples. (f) Comparison of expression of 27 PRGs between normal and LUAD samples. Log-rank test was performed in (b). Kruskal-Wallis test was performed in (e) and Wilcoxon test was performed in (f). ns, no significance. , , , .

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