circCCT3 Enhances Invasion and Epithelial-Mesenchymal Transition (EMT) of Non-Small-Cell Lung Cancer (NSCLC) via the miR-107/Wnt/FGF7 Axis

Figure 1

circCCT3 knockdown attenuated NSCLC invasion and EMT. (a) circCCT3 levels were measured by RT-qPCR in A549 and Calu-1 cells stably transfected with sh-NC, sh-circCCT3-1, and sh-circCCT3-2. , sh-circCCT3-1 vs sh-NC group, and sh-circCCT3-2 vs sh-NC group. (b, c) Cell invasion was examined in A549 and Calu-1 cells stably transfected with sh-NC, sh-circCCT3-1, and sh-circCCT3-2. , sh-circCCT3-1 vs sh-NC group, and sh-circCCT3-2 vs sh-NC group. (d, e) E-cadherin and vimentin levels were measured by RT-qPCR in A549 and Calu-1 cells stably transfected with sh-NC, sh-circCCT3-1, and sh-circCCT3-2. , sh-circCCT3-1 vs sh-NC group, and sh-circCCT3-2 vs sh-NC group.

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