Expression of CD47 in Endometrial Cancer and Its Clinicopathological Significance

Table 3

Univariate and multivariate analysis of the prognosticators of EC using TCGA data.

Characteristics	Total (n)	Univariate analysis		Multivariate analysis
		HR (95% CI)	P value	HR (95% CI)	P value
Clinical stage (stages I and II vs. stages III and IV)	542	3.270 (2.145–4.984)	<0.001	2.671 (1.266–5.637)	<0.001
BMI (>30 vs. ≤30)	519	0.967 (0.636–1.470)	0.876
Age (>60 vs. ≤60)	549	1.847 (1.160–2.940)	<0.010	1.301 (0.625–2.711)	0.482
Weight (>80 vs. ≤80)	528	1.060 (0.699–1.607)	0.784
Height (>160 vs. ≤160)	523	1.153 (0.758–1.753)	0.507
Histological type (mixed and serous vs. endometrioid)	552	2.628 (1.746–3.957)	<0.001	1.620 (0.772–3.402)	0.202
Histologic grade (G3 vs. G1 and G2)	541	3.281 (1.907–5.643)	<0.001	1.344 (0.618–2.923)	0.455
Tumor invasion (%) (≥50 vs. <50)	474	2.813 (1.744–4.535)	<0.001	1.222 (0.603–2.475)	0.578
Menopause status (post vs. pre and peri)	506	1.050 (0.507–2.175)	0.895
Diabetes (yes vs. no)	451	1.172 (0.731–1.878)	0.510
Hormones therapy (yes vs. no)	344	0.801 (0.380–1.689)	0.560
CD47 (low vs. high)	552	1.021 (1.010–1.032)	0.015	1.018 (1.007–1.029)	0.021