Combined Efficacy of CXCL5, STC2, and CHI3L1 in the Diagnosis of Colorectal Cancer

Table 3

Results for indicated biomarkers in the diagnosis of CEA-negative CRC from the non-CRC controls.

	Training set (n = 518, 167 CRCs vs. 351 controls)				Testing set (n = 206, 62 CRCs vs. 144 controls)
	AUC (95% CI)	Sensitivity	Specificity	Accuracy	AUC (95% CI)	Sensitivity	Specificity	Accuracy
CXCL5	0.834 (0.799–0.865)	0.695	0.869	0.813	0.834 (0.776–0.882)	0.710	0.861	0.816
STC2	0.874 (0.842–0.901)	0.862	0.849	0.853	0.898 (0.848–0.936)	0.930	0.801	0.842
CHI3L1	0.772 (0.734–0.808)	0.623	0.809	0.749	0.810 (0.750–0.862)	0.645	0.840	0.781
Model_2	0.938 (0.913–0.957)	0.826	0.917	0.888	0.961 (0.925–0.983)	0.887	0.931	0.918