Long Noncoding RNA MMP2-AS1 Contributes to Progression of Renal Cell Carcinoma by Modulating miR-34c-5p/MMP2 Axis

Figure 4

MMP2-AS1 promotes tumor growth of renal cell carcinoma cells by enhancing MMP2 expression. (a, b) The tumorigenesis analysis was performed in nude mice injected with CAKI-1 cells treated with MMP2-AS1 siRNA, or cotreated with MMP2-AS1 siRNA and MMP2 overexpressing plasmid. (a) The tumor images were shown. The levels of Ki-67 and PCNA were detected by IHC.

(a)

(b)