PTPN6-EGFR Protein Complex: A Novel Target for Colon Cancer Metastasis

Figure 3

Knockdown of PTPN6 inhibits colon cancer EMT in SW480 and LOVO cells. (a) In SW480 and LOVO cells, the expression of E-cadherin when PTPN6 is knocked down was detected by qRT-PCR. (b) In SW480 and LOVO cells, the expression of Vimentin when PTPN6 is knocked down was detected by qRT-PCR. (c) In SW480 and LOVO cells, the expression of N-cadherin when PTPN6 is knocked down was detected by qRT-PCR. (d) In SW480 and LOVO cells, the expression of Twsit1 when PTPN6 is knocked down was detected by qRT-PCR. (e) In SW480 and LOVO cells, the expression of Twist2 when PTPN6 is knocked down was detected by qRT-PCR. (f) In SW480 and LOVO cells, the expression of ZEB1 was detected by qRT-PCR when PTPN6 was knocked down. (g) In SW480 and LOVO cells, the expression of ZEB2 when PTPN6 is knocked down was detected by qRT-PCR. (h) In SW480 and LOVO cells, the expression of MMP2 when PTPN6 is knocked down was detected by qRT-PCR. (i) In SW480 and LOVO cells, the expression of MMP9 when PTPN6 is knocked down was detected by qRT-PCR. .

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)