Altered Expression of Survivin Variants S-2B and S-WT in Breast Cancer Is Related to Adipokine Expression

Figure 2

Relative expression of S-WT, S-2B, S-ΔEx3, LEP, and ADIPOQ in different BCa stages. Relative expression was compared among stages using the number of samples described for each gene in Table 2. Early stage patients exhibited the highest LEP expression (), and late stage patients showed the lowest expression levels (). On the other hand, we found the lowest S-ΔEx3 expression in patients with low-grade tumors () and a gradual increase, until reaching the highest expression in stage IIIB (15.39). Bars represent . .