Altered Expression of Survivin Variants S-2B and S-WT in Breast Cancer Is Related to Adipokine Expression

Figure 4

Correlation analysis between relative expression of survivin variants and adipokines in BCa. A random correlation analysis was performed to our set of studied genes. Each data point represents a sample where both genes were present in quantifiable levels. LEP and ADIPOQ show a strong positive correlation closely to a coefficient of 1. Similarly, S-2B and S-WT display a strong positive correlation. Furthermore, although some were moderate, we observed correlations such as the negative relationship of LEP with S-2B and S-WT and the negative relationship of ADIPOQ and these same two survivin variants. Lastly, we did not observe a correlation between the expression of adipokines and S-ΔEx3.