CircMAT2B Induced by TEAD1 Aggravates the Warburg Effect and Tumorigenesis of Oral Squamous Cell Carcinoma through the miR-942-5p/HSPD1 Axis

Figure 5

MiR-942-5p overexpression suppresses tumorigenesis and the Warburg effect in OSCC. (a): MiR-942-5p overexpression cell models were generated by infecting miR-942-5p mimic or its normal control into Cal-27 or HSC-6 cells and the expression of miR-942-5p was measured by qRT-PCR. (b) and (c): cell proliferation was detected by EdU assay (b) and (c). (d) and (e): cell migration was assessed by transwell migration assay (d) and (e). (f) and (g): cell invasion was measured by the transwell invasion assay (f) and (g). (h)–(j): The warburg effect relative glucose uptake (h), lactate production (i), and ATP levels (j) in OSCC cells. Each experiment was performed three times. Data are presented as mean ± SD. , , .

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