CircMAT2B Induced by TEAD1 Aggravates the Warburg Effect and Tumorigenesis of Oral Squamous Cell Carcinoma through the miR-942-5p/HSPD1 Axis

Figure 7

CircMAT2B accelerates OSCC progression through the miR-942-5p/HSPD1 axis. (a) and (b): cell models were constructed by transfecting Sh-NC, Sh-circMAT2B#1, Sh-circMAT2B#1 + LV-NC, Sh-circMAT2B#1 + LV-HSPD1 into Cal-27 or HSC-6 cells as indicated, transfection efficiency was assessed by qRT-PCR (a) and Western blotting (b). (c) and (d): Cell proliferation was detected by the EdU assay (c) and (d). (e) and (f) cell migration was assessed by the transwell migration assay (e) and (f). (g) and (h) cell invasion was measured by the transwell invasion assay (f) and (h). (i)–(k) Warburg effect relative glucose uptake (i), lactate production (j), and ATP levels (k) in OSCC cells. Each experiment was performed three times. Data are presented as mean ± SD. , , .

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