UHRF1 Induces Metastasis in Thyroid Cancer

Figure 3

UHRF1 increased the activation of c-Jun/AP-1. (a) BCPAP cells were cotransfected with UHRF1 and c-Jun/AP-1. The western blot was used to detect the expression of c-Jun and p-c-Jun. (b) BCPAP cells were cotransfected with c-Jun/AP-1 luciferase reporter, UHRF1, and c-Jun. Luciferase assay results are shown as a fold change of luciferase normalized to the c-Jun/AP-1 reporter and the vector plasmid alone. Data are the mean ± SD of three independent experiments, NS, not significant, , , by two-tailed Student’s t-test.

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