A Novel Prognostic Model for Acute Myeloid Leukemia Based on Gene Set Variation Analysis

Figure 7

Identification of key genes in prognostic gene sets. The PPI network of GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN (a) and HALLMARK_CHOLESTEROL_HOMEOSTASIS (b). The top 50 genes with the most nodes in the gene sets GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN and HALLMARK_CHOLESTEROL_HOMEOSTASIS are shown in (c) and (d), respectively. The DEGs of the high- and low-risk groups were obtained and intersected with the 50 candidate genes in each gene set (e, f). (g–j) The gene expression levels of TIMP1 and LDLR in GSE146173 and GSE12417.

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