LINC01087 Promotes the Proliferation, Migration, and Invasion of Thyroid Cancer Cells by Upregulating PPM1E

Figure 5

LINC01087 regulates PPM1E through hsa-miR-135a-5p. (a) Schematic diagram of the binding site of wild-type PPM1E and hsa-miR-135a-5p. (b) qPCR detection of the PPM1E expression after adding hsa-miR-135a-5p mimic. (c) Verify the binding of hsa-miR-135a-5p and PPM1E through dual fluorescein reporter gene test. (d) Detect the expression of PPM1E after LINC01087 knockdown by qPCR. (e) Use qPCR to detect the expression level of PPM1E in thyroid cancer tissues and adjacent tissues. (f) Use Pearson correlation to analyze the correlation between PPM1E and hsa-miR-135a-5p in thyroid cancer. .

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