Research Article

The Role of Ferroptosis-Related Molecules and Significance of Ferroptosis Score in Cervical Cancer

Figure 6

The regulation of erastin-induced ferroptosis by AC026790.1 (a∼c) The relative expression of AC026790.1, AC020907.1, and AC100847.1 in 20 pairs of CC tissues and their corresponding paracancer samples. (d, e) qRTPCR analysis was performed to detect the levels of AC026790.1 in Hela and Siha. (f, g) Overexpression of AC026790.1 transfected CC cells (Hela and Siha) were treated with different concentrations of erastin (0, 1, 2.5, 5, and 10 μM) for 24 h, and cell viability was detected by CCK-8. (h–j) Overexpression of AC026790.1 in SiHa and HeLa cells detected differences in ROS, Fe2+, and MDA between erastin-treated and NC groups. (, and ).
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