Research Article

Tetrahydrocurcumin Chemosensitizes Breast Cancer to Albumin-Bound Paclitaxel by Enhancing SPARC Expression through Demethylation

Table 2

Relationship between the expression Of SPARC protein and clinical pathology of patients with breast cancer.

(%)High (N)Low (N)

Age (year)≤4012 (7.59%)570.558
>40146 (92.41%)7670
Menopausal statusPremenopausal51 (32.28%)23280.311
Postmenopausal107 (67.72%)5849
TNM stageI-II124 (78.48%)66580.439
III-IV34 (21.52%)1519
Tumor size (cm)≤268 (43.04)40280.11
>290 (56.96%)4149
Lymph node metastasisNo72 (45.57%)5022<0.0001
Yes86 (54.43%)3155
Her2+No98 (62.03%)54440.073
Yes60 (37.97%)2436
ER+No89 (56.33%)42470.265
Yes69 (43.67%)3930
Triple-negative BCNo124 (78.48%)63610.848
Yes34 (21.52%)1816