Construction, Validation, and Visualization of Two Web-Based Nomograms for Predicting Overall Survival and Cancer-Specific Survival in Elderly Patients with Primary Osseous Spinal Neoplasms

Table 3

Univariate Cox analysis for OS and CSS of elderly patients with POSNs.

Variables	Univariate analysis for OS		Univariate analysis for CSS
	HR (95% CI)	value	HR (95% CI)	value
Age
61-70	Reference		Reference
71-80	1.12 (0.79-1.6)	0.521	0.51 (0.27-0.93)	0.030
>80	2.49 (1.71-3.63)	<0.001	1.72 (0.96-3.06)	0.067
Race
Black	Reference		Reference
Other	0.67 (0.29-1.55)	0.347	1.74 (0.41-7.35)	0.453
White	0.63 (0.35-1.14)	0.13	1.17 (0.36-3.75)	0.796
Sex
Female	Reference		Reference
Male	1.11 (0.82-1.5)	0.504	1.25 (0.77-2.04)	0.369
Histological type
Chordoma	Reference		Reference
Chondrosarcoma	1.33 (0.91-1.95)	0.136	1.68 (0.94-3.02)	0.081
Osteosarcoma	6.14 (3.81-9.89)	<0.001	4.56 (2.08-9.99)	<0.001
Other	4.25 (2.77-6.51)	<0.001	5.11 (2.65-9.85)	<0.001
Grade
I	Reference		Reference
II	1.73 (0.84-3.55)	0.138	7.41 (0.93-59.26)	0.059
III	4.4 (2.18-8.88)	<0.001	10.7 (1.31-87.17)	0.027
IV	7.07 (3.6-13.9)	<0.001	26.58 (3.54-199.59)	0.001
Unknown	2.11 (1.11-3.99)	0.022	8.56 (1.17-62.52)	0.034
T stage
T1	Reference		Reference
T2	1.48 (1.09-2.02)	0.013	1.83 (1.12-3)	0.017
T3	3.9 (1.88-8.07)	<0.001	6.48 (2.46-17.04)	<0.001
N stage
N0	Reference		Reference
N1	2.21 (1.2-4.07)	0.011	1.9 (0.69-5.23)	0.216
M stage
M0	Reference		Reference
M1	6.33 (4.24-9.46)	<0.001	9.29 (5.15-16.76)	<0.001
Marital status
Married	Reference		Reference
Unmarried	1.08 (0.79-1.47)	0.637	0.77 (0.46-1.28)	0.312
Tumor size (cm)
<6	Reference		Reference
6-12	1.16 (0.82-1.63)	0.395	1 (0.57-1.76)	0.999
>12	1.35 (0.88-2.07)	0.165	1.79 (0.94-3.4)	0.075
Surgery
No	Reference		Reference
Yes	0.38 (0.28-0.51)	<0.001	0.28 (0.17-0.45)	<0.001
Radiotherapy
No	Reference		Reference
Yes	1.49 (1.1-2.03)	0.01	1.49 (0.92-2.41)	0.108
Chemotherapy
No	Reference		Reference
Yes	2.22 (1.52-3.24)	<0.001	3.39 (2-5.73)	<0.001